Silo Pharma Announces Provisional Patent Filing For SPC-15 Targeting NMDARs And 5-HT4Rs For Stress-Induced Psychiatric Disorders; Advances Collaboration With Columbia University

Silo Pharma, Inc. (NASDAQ:SILO) ("Silo" or the "Company"), a developmental stage biopharmaceutical company focused on novel therapeutics and drug delivery systems, today announced the filing of a provisional patent application with the U.S. Patent and Trademark Office (USPTO). This application, focused on its lead asset SPC-15, highlights Silo's commitment to advancing treatments for stress-induced psychiatric disorders, including post-traumatic stress disorder (PTSD).

The provisional patent covers the chronic, combinatorial targeting of N-methyl-D-aspartate receptors (NMDARs) and serotonin type IV receptors (5-HT4Rs) to extend behavioral effects against stress-induced perseverative behavior and hyponeophagia. This filing adds to Silo's growing portfolio of pending patents for SPC-15 technology, originally licensed through a collaboration with Columbia University. This exclusive agreement enables Silo to develop, manufacture, and commercialize SPC-15 globally.